A previous systematic review demonstrated that genetic variations within MICB (meta-OR=2.35, 95% CI: 1.68–3.29), MBL2 (meta-OR=1.54, 95% CI: 1.02–2.31), and IFN-γ (meta-OR=2.48, 95% CI: 1.30–4.71) are associated with dengue25; however, it did not differentiate between severe dengue and classic dengue or asymptomatic dengue. Here, MICB is linked to dengue disease.