SLC25A46 and Leber hereditary optic neuropathy: In addition, the mutations found in nuclear genes such as NDUFS2, OPA1, NDUFS7, MTFMT, PDSS1, NDUFV1, NDUFA3, DNAJC30, SLC25A46, SLC25A3 and MYOC extend our understanding of the genetic landscape of LHON.