In lipopolysaccharide-induced AKI, the expression of miR-124-3p.1 targeting LPCAT3 is decreased, leading to an increase in LPCAT3 activity and, subsequently, an elevation in phosphatidylcholine content in TECs, inducing cellular lipid peroxidation and ferroptosis (Zhang et al., 2022). The gene discussed is LPCAT3; the disease is acute kidney injury.