IL1B and Ureteral obstruction: In the kidney, cellular pyroptosis can be induced by various factors, such as cadmium, contrast agents, renal ischemia-reperfusion, and unilateral ureteral obstruction, characterized by the activation of inflammatory caspase cysteine-dependent aspartate proteases and the release of interleukin-1 beta (IL-1β) (Liu et al., 2022).