NHLRC2 and Sepsis: To investigate whether the five identified genes are involved in the regulation of aforementioned pathways, we divided all sepsis samples with clinical outcomes into high and low expression groups based on the median expression levels of the five genes: GTPBP2, ALDOA, PRKAR2A, KIF2C, and NHLRC2. The GTPBP2 overexpression group exhibited enrichment in the platelet activation, signal transduction, and aggregation pathways (Figure 2B).