According to the findings, the major genes influencing sepsis prognosis were GTPBP2, ALDOA, PRKAR2A, KIF2C, and NHLRC2. Since antiplatelet drug (aspirin, clopidogrel and indobufen) possesses antiplatelet and antiaggregation properties, we performed molecular docking of these genes with aspirin using Autodock to confirm their interaction. This evidence concerns the gene GTPBP2 and Sepsis.