Furthermore, some lncRNAs participate in the progression of diabetic complications, such as plasma taurine upregulated gene 1 (TUG1) which is associated with the progression of diabetic nephropathy in diabetic rats and Kcnq1ot1 which is involved in the progression of diabetic cardiomyopathy (Yang et al., 2018a). This evidence concerns the gene TUG1 and diabetic kidney disease.