AKT1 and melanoma: Up-regulated and down-regulated DEGs were significantly enriched in cell cycle, PI3K-Akt signaling pathway, progesterone-mediated oocyte maturation, p53 signaling pathway, cellular senescence, oocyte meiosis, melanoma, FoxO signaling pathway, AMPK signaling pathway, EGFR tyrosine kinase inhibitor resistance, fatty acid degradation, antifolate resistance (Figure 3D).