Previous studies have shown the association of SNPs in PTX3, mainly rs1840680 and rs2305619, with susceptibility to infectious diseases such as Pseudomonas aeruginosa in patients with cystic fibrosis [11], Aspergillus fumigatus in patients undergoing hematopoietic stem cell transplantation [12], fungal infections in solid organ transplant patients [13], urinary tract infections [14], and pulmonary infection by Mycobacterium tuberculosis [10, 21]. Here, PTX3 is linked to fungal infectious disease.