OFD1 and orofaciodigital syndrome I: The presumed X-linked condition Aicardi, where the disease-causing gene is unknown, the X-linked dominant orofaciodigital syndrome caused by pathogenic variants in OFD1, and the autosomal recessive Chudley–McCullough syndrome with pathogenic GPSM2 gene variants often have interhemispheric ACs in addition to other symptoms [16–19].