AHSG and type 2 diabetes mellitus: We find that genetically predicted fetuin-A increases the risk of coronary artery disease in individuals with type 2 diabetes (OR = 1.59, 95% CI 1.01–2.50, P = 0.04), but we do not find such an association between genetically predicted fetuin-A and coronary artery disease in individuals without type 2 diabetes (OR = 0.97, 95% CI 0.84–1.12, P = 0.65; P for interaction = 0.03).