Scatterplots, forest plots, funnel plots and leave-one-out plots of the two-sample MR analyses are provided in Supplementary Figs. 2, 3, 4 and 5.We did not find evidence for an association between genetically predicted fetuin-A and coronary artery disease (OR = 1.00, 95% CI 0.95–1.06, P = 0.91) in the combined cohort of individuals with and without type 2 diabetes. Here, AHSG is linked to coronary artery disorder.