In the leave-one-out analysis, we find that the effect of genetically predicted fetuin-A on type 2 diabetes is no longer significant if SNP rs11017848 is excluded (OR = 1.178, 95%CI = 0.893–1.554, P = 0.247; Online Table 3 and Supplementary Fig. 2). This evidence concerns the gene AHSG and type 2 diabetes mellitus.