The nine SNPs included in the 278 PCa risk allele panel showed non-significance (all P > 0.11), while the top associated known cancer variants were rs1859962 in CASC17 (P = 0.003; OR 1.49, 95% CI: 1.142–1.93) and rs3734805 in CCDC170 (P = 0.004; OR 2.0, 95% CI: 1.244–3.2) (Fig. 4B). Here, CASC17 is linked to posterior cortical atrophy.