RPLP2 is highly expressed in gynaecological tumours, colon cancer, and lung adenocarcinoma [23–25], and a lack of RPLP2 leads to the accumulation of reactive oxygen species (ROS) and activation of the MAPK1/ERK2 signalling pathway, which induces cancer cell cycle arrest and autophagy [18]. The gene discussed is RPLP2; the disease is colonic neoplasm.