Figure 1G demonstrates the localization of COL1A1, PTPRC (CD45), KRT1, and CDH5 (vascular endothelial cadherin). Immunohistochemistry (IHC) corroborated this layered arrangement of infiltrating immune cells and stromal cells centering around a ruptured tunnel or abscess (Figure 1H). The gene discussed is CDH5; the disease is abscess.