IL4R and myocardial infarction: In agreement with HW/BW findings, cardiac volume measured by echocardiography showed that IL-4RαMacKO had more dilated hearts at 28 dpi than control mice only after MI (Supplemental Figure 4, D and E), suggesting than lack of IL-13/IL-4Rα macrophage activation after MI has an aggravating effect on cardiac remodeling and dilation.