Immunoblotting analysis further confirmed that the tissue homogenates of the inflamed‐BPH groups displayed elevated levels of total and nuclear YAP1 proteins, as well as the downstream protein, connective tissue growth factor (CTGF), which is known for its pro‐fibrotic and ECM remodeling effects (Figure 1H). The gene discussed is CCN2; the disease is benign prostatic hyperplasia.