NPPB and hydrops fetalis: Once AHF patients are stabilized, the recent “The Safety, Tolerability and Efficacy of Rapid Optimization, Helped by NT-proBNP Testing, of Heart Failure Therapies” (STRONG-HF) study has revealed that an intensive strategy of HF therapies (including BB) initiation before hospital discharge with a rapid up-titration within the first 6 weeks was safe and reduced 180-day all-cause mortality and re-hospitalization for HF (42).