The All of Us (AoU) Research Program demonstration project used BMI, WC, WHR, and alanine aminotransferase (ALT) to assess racial, ethnic, and gender differences in obesity and body fat distribution in 88,195 NHW, 40,770 NHB, 35,640 Hispanic, and 5,648 Asian participants. This evidence concerns the gene GPT and obesity due to melanocortin 4 receptor deficiency.