MLL rearrangements can occur with approximately 80 different partner genes.[13] In MLL-rearrangement (MLL-r) AML, the most common fusion partners are AF9 and AF6, resulting in the translocations t (9;11) (q22; q23) and t (6;11) (q27; q23) respectively. The gene discussed is MLLT3; the disease is acute myeloid leukemia.