FXR1 is primarily found in the nervous system and muscle tissue, playing an important role in normal muscle growth and myogenesis.[3–5] Recent studies have revealed that FXR1 plays a crucial role in the advancement of tumors and is linked to unfavorable outcomes in a range of human cancer types, such as breast, ovarian, head and neck, and non-small cell lung cancers.[6–8] In non-small cell lung cancer, FXR1 is overexpressed in tissues and cells. This evidence concerns the gene FXR1 and cancer.