According to the chi-squared test, the expression of ITLN-1 was significantly correlated with tumor size (P < .001), degree of pathological differentiation (P < .001), vascular invasion (P < .001), degree of cirrhosis (P < .001), capsule status (P < .001) and recurrence (P < .001), but not with gender, age, AFP, tumor stage, or hepatitis B surface antigen. This evidence concerns the gene ITLN1 and neoplasm.