ITLN1 and hepatocellular carcinoma: Multivariate analysis confirmed that ITLN-1 expression was an independent prognostic factor for OS, and the OS rates of HCC patients with low expression of ITLN-1 after hepatectomy were 92.3, 57.0 and 31.5%, which was significantly lower than those of HCC patients with high expression of ITLN-1 (HR, 0.513; 95% CI, 0.283–0.929 P = .046) (Table 4 and Fig. 5A).