INS and diabetes mellitus: The reported more pronounced effect of CM on patients with T1D in normalizing blood lipids is consistent with findings of our meta-analysis on the effect of CM on glucose homeostasis in patients with diabetes, where the insulin dose for patients was significantly decreased by the consumption of CM (MD, − 16.72, 95% CI: −22.09, − 11.35 p < 0.00001, I2 = 90%) in comparison with the controls [16].