Moreover, the MAGMA gene-set enrichment analysis identified characteristic biological processes for these mental disorders, including energy metabolism-related processes (“cAMP catabolic process”, “electron transport”, “cytochrome c to oxygen”, and “thyroid hormone catabolic process”) in ASD, and pathways of amino-acid metabolism (“fatty acid homeostasis”, “aspartate metabolic process” and “aspartate biosynthetic process”) and neuronal signals (“cerebral cortex GABAergic interneuron fate commitment”) in adult-SCZ (Additional file 1: Fig. S12a-b). This evidence concerns the gene CYCS and mental disorder.