Based on univariate Cox regression, six genes (PPM1G, FKBP1A, STAM, MAD2L2, TBL1XR1, and ANXA5) were selected from 51 CD8+ TEX-related DEGs using LASSO regression analysis, and a prognostic risk score model of HCC was constructed (Fig. 2A, B). This evidence concerns the gene TBL1XR1 and hepatocellular carcinoma.