LOX and urogenital neoplasm: Moreover, 12/15 LOX and its metabolites 12(S)-HETE and 15(S)-HETE are known to induce ER stress, cell death (Elmasry et al. 2018; Li et al. 2018) and inflammation (Kulkarni et al. 2021; Kar et al. 2020; Faulkner et al. 2015), all of which are commonly observed in the post-ischemic kidney and have been implicated in disease progression (Inagi 2010; Linkermann et al. 2014; Shu et al. 2018).