Using polysome analyses (Fig. 7f and Extended Data Fig. 10e), to fractionate mRNAs based on their translational efficiency62, we confirm that IKZF3 mRNA indeed has lower translational efficiency in both PAX5-TSS2mut lymphoma cells (Fig. 7g) and in ZCCHC7-OE lymphoma cells (Extended Data Fig. 10f,g), compared to parental SUDHL10 lymphoma cells. Here, ZCCHC7 is linked to lymphoma.