PAX5 and diffuse large B-cell lymphoma: Supporting this possibility, we observe that PAX5 and ZCCHC7 gene promoters exist in the same TAD in mice (Extended Data Fig. 3e) and humans (Fig. 5d)35 and that PAX5 and ZCCHC7 expression is negatively correlated in DLBCL cell lines (Extended Data Fig. 4a).