These anatomical changes observed in the present study suggest that our PCP model exhibits attenuated excitatory inputs from other cortex in the PL, which is consistent with the morphological features observed in patients with schizophrenia, such as reductions in dendritic spines [43–45, 50] and VGLUT1 [51, 52] in layer 3 of the DLPFC. The gene discussed is SLC17A7; the disease is schizophrenia.