MYCN and neuroblastoma: Lastly, we found that MYCN-amplified (SK-N-BE(2)-C, CHP-134, KELLY and IMR-32) human neuroblastoma cell lines had significantly higher SNRPD3 expression when compared to MYCN non-amplified cell lines (SK-N-AS and SH-SY5Y) and human fibroblast (MRC-5 and WI-38) cell lines (Fig. 1I and Supplementary Fig. 1J).