In addition, we collected tissue specimens from 32 female advanced CRC patients at the Second Affiliated Hospital of Nanchang University, and the result of qRT-PCR also showed that the expression level of CCL22 (Fig. 12H) was lower in female advanced CRC tissues than adjacent tissues, whereas the expression level of CCL19 (Fig. 12G), CCR9 (Fig. 12I), CX3CL1 (Fig. 12J), XCL1 (Fig. 12K), and CXCR5 (Fig. 12L) were higher in female advanced CRC tissues than adjacent tissues. The gene discussed is XCL1; the disease is colorectal carcinoma.