As shown in Fig. 7A, GSEA analysis based on hallmark gene sets suggested that the tumor-promoting pathways (i.e., WNT_BETA_CATENIN_SIGNALING) were enriched in the high-risk group, whereas abundant anti-tumor immune response-related pathways (i.e., ALLOGRAFT_REJECTION, IL2_STAT5_SIGNALING, and IL6_JAK_STAT3_SIGNALING) and inflammatory response-related pathway (i.e., INFLAMMATORY_RESPONSE, INTERFERON_GAMMA_RESPONSE, and INTERFERON_ALPHA_RESPONSE) were enriched in the low-risk group. Here, STAT3 is linked to neoplasm.