Meanwhile, this study also found that CPA4 is clinically associated with poor prognosis in various tumours, and in liver cancer tissue, the expression of CPA4 protein is negatively correlated with the expression of PP2A and the cleavage of GSDME, while it is positively correlated with the expression of p-AKT (Fig. S6). The gene discussed is CPA4; the disease is neoplasm.