• AML患者危险度在预后良好组中CEBPA双突变更新为CEBPA bZIP框内突变,预后不良组中增加了BCOR、EZH2、SF3B1、SRSF2、STAG2、U2AF1、ZRSR2基因突变及t(8;16)(p11; p13)/KAT6A::CREBBP和11p15/NUP98基因易位。. The gene discussed is U2AF1; the disease is acute myeloid leukemia.