The radiation treatments cause ubiquitous DNA damage in cancer cells, but the aberrantly upregulated DNA repair features attenuate DNA injuries and cause critical resistance to RT.[5] RAD51 is a highly conserved protein that regulates DNA repair via homologous recombination, which promotes replication restart and provides error‐free repair of DSBs.[6] Bioinformatics analyses of GBM patients revealed the abnormal upregulation of RAD51 in glioblastoma tissues when compared to that in normal brain tissues (Figure 1A). The gene discussed is RAD51; the disease is cancer.