Moderate correlations were found between S-calprotectin and B-WBC, SF-WBC, B-ESR, S-anti-CCP2, S-IgM-RF, DAS28-CRP, DAS28 and SJC, and weak correlation observed between S-calprotectin and SF-MNC, HAQ and TJC in patients with anti-CCP2 positive RA (Table 2). The gene discussed is CRP; the disease is rheumatoid arthritis.