Compared to the non-infection group, we observed elevated levels of the majority of measured cytokines (25/48) in the CSF during Mtb infection, including TNF-α, IFN-γ, IL-1β, IL-2, IL-3, IL-6, IL-8, IL-10, IL-12(p40), IL-17A, IL-18, IP-10, MIG, MCP-3, MIP-1α, and MIP-1β. The gene discussed is IL1B; the disease is infection.