Figure 3C shows the six most significantly enriched pathways and the DEGs with which they overlap; Fig. 3D shows the two pathways associated with cardiac hypertrophy. In addition, the DEGs most frequently occurring in the predicted pathways were identified: Pik3c2a (24/26 pathways), Sos1 (20/26), Sos2 (18/26), Mapk8 (17/26), Jun (12/26), and Atf2 (10/26). The gene discussed is SOS1; the disease is cardiac hypertrophy.