HMGB1 and neoplasm: The enzyme-linked immunosorbent assay (ELISA) assays measuring serum markers of damage-associated molecular pattern, such as decorin (DCN) (Figure 6I)19 and high mobility group box 1 (HMGB1) (Figure 6J),53 also provided support for the enhancement of ferroptosis-mediated tumor suppression in vivo through TXNDC12 knockdown.