Boultwood J, Yip B H, Vuppusetty C, et al. Activation of the mTOR pathway by the amino acid L-leucine in the 5q syndrome and other ribosomopathies[J]. Advances in biological regulation, 2013, 53(1): 8–17. Here, MTOR is linked to myelodysplastic syndrome associated with isolated del(5q).