Among the top 100 coexpressed genes with ARHGAP11A and ARHGAP11B, there were several genes in common, and most of them are involved in breast cancer, including (genes that contributed to breast cancer are shown with their corresponding references) BUB1B [38, 39], BUB1 [38, 40], KIF20A [38, 41], ASPM [42], TOP2A [43], CKAP2L [44], KIF23 [45], NUSAP1 [46], PRC1, SGOL1 [47], KIF11 [48], MKI67 [49], NCAPH [50], POLQ [51], RACGAP1 [52], KIF14 [53], KIF15 [54], MCM10 [55], CENPF [56], CASC5, STIL, CENPI, PLK4 [57], E2F8 [58], CLSPN [59], and GSG2 [60]. The gene discussed is TOP2A; the disease is breast cancer.