Moreover, we looked for GSEA using LinkedOmics which revealed some similar BP terms and KEGG pathways for them, representing similar roles for ARHGAP11B in BLBC malignancy through the ER or HER2 receptor signaling pathways due to its expression correlation with ARHGAP11A. However, it needs more research to uncover the exact molecular mechanisms of ARHGAP11B in BC. This evidence concerns the gene ESR1 and breast cancer.