It has a high affinity with albumin and usually binds to albumin in the blood to form water-soluble complexes, which are transported to the liver for excretion.1,2 In the case of liver damage or metabolic obstruction, the concentration of bilirubin in the body will sharply increase, known as hyperbilirubinemia. The gene discussed is ALB; the disease is Hyperbilirubinemia.