Similarly, while there was no discernible difference in the distribution of allele frequencies of the interleukin-1b promoter, interleukin-1b exon 5, interleukin-6 promoter, interleukin-8, interleukin-10, or the tumor necrosis factor α gene polymorphism (104 patients with FS and 143 healthy controls), Chou et al. reported that patients with FS were more likely to have the interleukin-1 receptor antagonist allele 1 homozygous [11,12]. This evidence concerns the gene IL6 and Feingold syndrome.