MDSCs have several chemokine receptors, including CCR1, CCR2, CCR3, CCR5, CCR12, CXCR2, CXCR4, and C5aR1.25In the current study, MDSCs may express CCR1, the receptor of CCL9, which mediated the migration of MDSCs to tumor tissue. Here, CXCR4 is linked to neoplasm.