PTH and parathyroid gland carcinoma: Cinacalcet has been tried in cases of parathyroid carcinoma, with a transient reduction in serum calcium level.24,25 One case report has described the efficacy of octreotide, a long-acting somatostatin analogue, in a woman with parathyroid carcinoma and metastatic bone disease, where they show a transient decrease in PTH levels.26 Synthetic oestrogen has been found to be successful in a single case.27 Immunization with human and bovine PTH peptides with booster doses at 4 and 11 weeks helped lower serum calcium levels for 6 months in a patient with parathyroid carcinoma.28,29