Remarkably, the YAP1 and WWTR1 genes, which code for YAP and TAZ respectively, undergo amplification in approximately 14% of head and neck squamous cell carcinomas (HNSCCs), around 16% of lung squamous carcinomas, approximately 17% of cervical squamous cell carcinomas, and about 15% of esophageal squamous cell carcinomas.103. The gene discussed is WWTR1; the disease is esophageal squamous cell carcinoma.