Protein involved in the antigen processing (Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B, Heat shock 70 kDa protein 6) and respiratory burst (Neutrophil cytosol factor 2 - NCF2), were also increased in the macrophage during infection with P. brasiliensis.Figure 5 shows an overview of the proteome changes observed in THP-1 macrophages exposed to P. brasiliensis. The gene discussed is HSPA6; the disease is infection.