Unexpectedly, the predominant functional networks (mapped by STRING)31 overrepresented by the aforementioned AD-phenotypic G9a interactors were primarily associated with major translational or post-translational processes such as alternative splicing, RNA modification and processing, translation initiation and elongation, ribosome biogenesis, and protein degradation (proteostasis22) (Fig. 1B). The gene discussed is EHMT2; the disease is Alzheimer disease.