This population was characterized by relatively high levels of expression of Granzyme B, interleukin 7 receptor (IL-7R, CD127), leukocyte antigen B associated transcript 3 (Bat3), and PD-L1 as well as relatively low levels of CD69 compared to the terminally differentiated putative anti-tumor CD8+ T cell population – an overall profile consistent with the presence of anti-viral effector CD8+ T cells. This evidence concerns the gene CD274 and neoplasm.