Immune checkpoint molecules (PD-1, PD-L1, PD-L2) and immune suppressor markers (Tim-3, FOXP3, LAG3) were all significantly expressed on tumor T-cells as well as co-stimulatory molecules (STING, B7-H3, OX40L, 4-1BB). This evidence concerns the gene PDCD1LG2 and neoplasm.