In nasopharyngeal cancer NPC-TW 039 cells, a concentration of 8 μM tetrandrine hindered cell viability and rendered G0/G1 period cell cycle arrest; it also induced apoptosis through a pathway involving calcium-mediated ERS and caspase, the mechanism of which was mainly due to the production of ROS and Ca2+ caused by powdered antibiotics, leading to intracytoplasmic Ca2+ release, ERS promotion, and enhanced expression levels of relevant proteins such as GADD153 and GRP78 (Liu K. C. et al., 2017). Here, DDIT3 is linked to nasopharyngeal carcinoma.