DDIT3 and gastric cancer: Schizandrin A at 30 μM notably enhanced the level of the ERS receptor GRP78 protein in AGS gastric cancer cells and caused apoptosis by inducing phosphorylation of the eIF2α and PERK signaling pathways, along with upregulating the level of CHOP and promoting the ERS-mediated apoptosis pathway (Pu et al., 2021).