Notably, patients deficient in glucose 6‐phosphate dehydrogenase, the first enzyme of the oxidizing branch of the pentose phosphate pathway, exhibit diminished NADPH and ROS levels, making them more susceptible to bacterial infections.[84] Additionally, MPO deficiency in humans is primarily linked to recurrent fungal infections,[85] which is supported by similar findings in MPO‐deficient mice. Here, MPO is linked to fungal infectious disease.