We found substantial variation in test sensitivity to detect anaemia and severe anaemia, with lowest values reported for HCS and Rad-67.(29, 58) This is contrary to a previous review that identified lowest sensitivity to detect anaemia for HemoCue301 (22.6%) and highest sensitivity for HCS (99.3%) out of 6 POC(Hb)Ts.(81) Our median values for test sensitivity and specificity to detect anaemia were moderate, suggesting some children would receive a false negative result. This evidence concerns the gene GSTM1 and anemia (phenotype).