CD4 and sexually transmitted disease: Clinically, the participants presented a median plasma viral load (VL) of 37,313 HIV RNA cp/ml (interquartile range (IQR): 5,849–126,162), median CD4 count of 445.5 cells/cc (IQR: 357–613), 54% had an additional STI diagnosis at enrollment, and almost 40% reported acute HIV symptoms, such as fever, fatigue, headache, sore throat, muscle pain, lymphadenopathy, and skin rash, before (12.6%) or at (27.2%) enrollment.