PADI4 and Alzheimer disease: Of the genes associated with both IL-7Rαlow EM CD8+ T cells and AD (as per the 3 publicly available AD peripheral blood microarray datasets evaluated for this study), PADI4 was found to be differentially expressed among the three clinical groups though adjusted P-values from post-hoc multiple comparison testing did not reach statistically significant levels between clinical groups (Fig. 2B).